Lopini and his brothers, Lelea and Mickey, played in the junior grades for the Roosters and have all played for the Newtown Jets. Lopini and Mickey were members of the 2006 Newtown side that played were beaten by 1 point by Parramatta in the grand final.
Won NRL selection with the Sydney Roosters in 2003 and played in the premiership-winning 2004 Roosters reserve grade.
Representative honours: 2007 Junior Kangaroos. Captained Tonga in the 2008 Rugby League World Cup.